Sentence examples for most downregulated microRNAs from inspiring English sources

Both miR-27b and miR-181b were among the most downregulated microRNAs in parous compared to nulliparous ALDH positive MECs.

According to a previous study [ 24], the expression of the most downregulated microRNAs in smokers was restored one week after smoking cessation.

For visualization of global microRNA::mRNA interactions in ULMs, box plots were used as a convenient way of graphically depicting the regulation of the mRNA targets of the 5 most highly upregulated and 5 most downregulated microRNA.

The most significantly downregulated microRNAs in BRAFwt compared to BRAFmut PTCs was mir492 and the most upregulated one was mir32.

MiR-17 and miR-20a belong to the medium abundant microRNAs in native USSC and they are found among the most strongly downregulated microRNAs in XXL-USSC, together with miR-106b.

Among them, miR-639 and miR-1200 were the most remarkably downregulated microRNA in SCC9 (TGFβ) cells (Table S1).

In conclusion, from our systematic review study we identified that miR-21 is the most consistently reported upregulated microRNA and miR-375 is the most consistently reported downregulated microRNA in gastric cancer.

The downregulated enrichment or DRE ranks from most downregulated to the least downregulated.

Notably 5 microRNAs (miR-200a,b,c and miR-34b,c), including those most downregulated in the tumors, correlated to NOTCH signaling and directly targeted NOTCH1 in in vitro experiments using SH-SY5Y neuroblastoma cells.

The pathway gene sets most downregulated with increasing emphysema severity, including those involved in ECM maintenance, were anti-correlated with upregulated microRNA expression.

Only the top 50 (25 most upregulated and 25 most downregulated) were selected at this stage.