Sentence examples for most downregulated in from inspiring English sources

We found that among highly expressed antigen-presentation-related genes (coding for cathepsin D, TAPL, V-ATPase subunits), the calcium sensor Stim1 gene was one of the most highly expressed in WT spleen (Fig. 3a) but also the most downregulated in 3d/3d spleen compared to WT (Fig. 3b).

Among six miRNAs, we focused on miR-148a because its expression was most downregulated in GC tissue.

Those most downregulated in SAMP8 and not restored by CR were processes associated with immunological function and mitosis (Fig. 1C).

The PPARG, RXRA, GATA2, GATA3, FOXA1 and ELF3 transcription factors genes were among the most downregulated in the SCCL-down list (Fig.  1a, Additional file 2: Table S2).

Thus, the genes that were most downregulated in females were predominantly involved in oogenesis – including chorion formation and cell division functions – which is consistent with defective oocyte development.

In our microarray, we identified the RXR gamma isoform as the most expressed in the rat myocardium and the most downregulated in AR (not shown).

Most downregulated genes in in vitro were also repressed in vivo.

Thus, CTCFL can act on male-specific germ cell genes in ES cells, and two of the most downregulated genes in CTCFL-deficient testis are upregulated in CTCFL-GFP-V5-expressing ES cells.

The most downregulated gene in the Calvin cycle in glu1-2 leaves is encoding a putative fructose-biphosphate aldolase (At4g26530).

The differentially expressed gene list for each OS region demonstrated highest upregulated gene expression in the cornea and most downregulated genes in LEC.

This confirms that ESR1 was one of the most downregulated genes in MCF7 following DAC treatment, and upregulated in MDA-MB-231 s, but also identifies other genes, including several histone proteins, that are similarly downregulated upon DAC treatment.