Sentence examples for most downregulated clusters from inspiring English sources

In contrast, the most downregulated clusters were enriched with genes related to lipid, nucleotide, and amino acid metabolism.

The two genes demonstrating the greatest downregulation in ethanol-reared larvae both encode triglyceride lipases (CG6277, 216-fold; CG6283, 163-fold), and three of the top 11 most downregulated genes fall into this cluster.

The downregulated enrichment or DRE ranks from most downregulated to the least downregulated.

Amongst others, this cluster includes the mRNA encoding plasmid SOS inhibition protein A (PsiA), and the most downregulated and subsequently upregulated mRNA, which encodes a putative transposase (PSL035).

Interestingly, the most downregulated miRNA was mir-92a-5p, which along with miR-18a (also down-regulated), are encoded by the miR-17∼92 miR-17∼92hose overexpression has been linked to tumorigenesis and poor prognosis in MM.

The miRNAs encoded by miR-17-92 miR-17-92 miR-17-92the paralogous miR-106b-25 clusters were identified to be asong most abundant miRNAs in undifferentiated PUER cell, welle they were asong the most downregulated miRNAs uparalogousell differentiation (Supplementary Tables 1 and 2).

Only the top 50 (25 most upregulated and 25 most downregulated) were selected at this stage.

And skeletal muscle functional genes enriched in several downregulated clusters are shown in Fig. S5B and S5C.

Hypocretin was the most downregulated gene in human narcolepsy brains.

Because of the sequence divergence between Spr and B6, the substantial number of downregulated probes and downregulated clusters might reflect this divergence and not the decreased expression.

Enrichment analysis was done separately for each cluster in the heatmap, for all up- or downregulated clusters, and for all clusters combined.