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The method permits interpolation in every point within most domains, while preserving the maximum and minimum principles.
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Moreover, these domain combination networks are known to exhibit small-world and scale-free topologies, where a few domain superfamilies are connected to many different domains, while most domains are adjacent to only one or two types of neighbors [ 7, 8].
While we report on improvement across most domains of function, we did not observe this for learning or psychomotor processing.
But the same is true of most domains, including business.
Teams considered disease burden, needs of information, feasibility and effectiveness as the most relevant domains, while health promotion and adverse events were considered the least important.
"Training," "Performance Monitoring," and "Leadership that Reinforces Learning" were characterized as the most favorable domains, while "Time for Reflection" was the least favorable.
While most domain families are relatively small (less than 15 copies per species), a few are very large (see Figure S1 in Additional file 2).
In the case of polymorphic toxins the domain architecture template is defined by the presence of multi-domain proteins, wherein the C-terminal-most domain has toxin activity, while the N-terminal-most domains are associated with trafficking (Table 1, Figure 1).
From the presented results, it can be seen that the proposed approach achieves high values for both overall classification accuracy and average precision for τ = 0 in all selected domains, while most of the supported classes exhibit increased recognition rates.
Members of both AGO and Piwi subfamilies possess the characteristic DDH metal binding signature residues in their Piwi domains, while most of the WAGO proteins lack them.
Members of Group 1 typically contain two WRKY domains, while most proteins with one WRKY domain belong to Group 2. Group 3 proteins also have a single WRKY domain, but the pattern of the zinc-finger motif is unique.
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