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In accord, the LTSP group has experienced the strongest purifying selection among the three groups, shows the highest and most diverse expression patterns, and includes most A. thaliana FBX loci previously demonstrated to control key processes in plant biology (Tables S3 and S4).
Among the GmRR genes, the type-A GmRRs possessed the most diverse expression levels in both roots and shoots (Fig. 1C).
Most diverse expression patterns were found in the members of CC-type GRX genes, indicating that this class of proteins are most evolved with specialized function.
As it was shown for the full transcriptomic analysis on the pig ESTs, the most diverse expression is in brain and testes tissues [ 12] and particular brain and developmental tissues hold a relatively higher expression of putative ncRNAs [ 13].
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Overall, the brain displayed the most diverse miRNA expression and had the largest number of tissue-enriched miRNAs.
The miRNAs that showed an upregulation with mTEC maturation were of particular interest in the context of this study, since mature CD80high/MHCIIhigh mTECs are characterised by the highest and most diverse promiscuous expression of TRAs [ 8].
Most of genes exhibited diverse expression profiles among different organs.
Principal component analysis (PCA) of gene expression in the spleen (Figure 2B) showed that early (day 7) iCT frogs contributed the most diverse patterns of gene-expression of any group, as well as showing the highest prevalence and intensities of infection (Figure 1).
Taken together, their diverse expression is most likely involved in determining tumor phenotype, i.e. associating higher proportions of the poorly differentiated carcinomas or the highly differentiated papillary adenocarcinomas with the expression of STAT5Δ750 or STAT5ca, respectively [ 15].
In many cancer-related microarray experiments (see Introduction section), P-DUDES genes showed diverse expression changes, although most often SRPX and CCD80 were downregulated whereas SRPX2 was upregulated.
Our RT-PCR results showed that most of the VvAP genes exhibited diverse expression levels in all six organs, indicating these APs often participate in plant development.
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