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Exact(5)
By this approach, the most distant pair of taxa is excluded from the splits network, and the midpoint root is recalculated.
Excluding the most distant pair in each step results in smaller distances as the iterations proceed (supplementary table S3, Supplementary Material online).
The most distant pair of sequences in the entire P1 set (YP_004138486 vs. YP_003007995, COG0221) has three indels within 175 amino acid protein sequence alignment and has a reported BlastP e-value of 4 × 10− at 28% sequence identity.
These parameters can be compared to the longest MFPT within a network of states (nodes), which usually refers to the passage time, counted in the random walker steps, between the most distant pair of nodes.
Progressive multiple sequence alignment algorithm is a heuristic alignment technique that builds up a final multiple sequence alignment by combining pair-wise alignments starting with the most similar pair and progressing to the most distant pair.
Similar(55)
With this definition one of the most distant pairs considered was Escherichia coli and Vibrio Cholerae.
Of the 100 families, in 16 these most distant pairs show signs of XGD, that is, the genes from these pairs belong to distant clades.
In terms of structural comparisons, both Y- and S/C-GSTs are extremely similar; structural superpositions, even between the most distant pairs of GSTs, are highly significant.
> -wrap-foot> To quantitatively assess the contribution of XGD to the observed variance of the relative evolutionary rates, we reconstructed phylogenetic trees for all genes in the P1 set and examined the positions in these trees of the most distant pairs of orthologs that appear to be prime suspects for XGD (supplementary data S4, Supplementary Material online).
Synteny between all genomes is extensive, and even within the most distant genome pairs over 90% of orthologous gene pairs are followed by another pair of orthologous genes.
The average distance between markers was 13 cM, ranging from 0 cM for the closest marker pairs to 243.3 cM for the most distant marker pairs.
Related(20)
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