Sentence examples for most disordered regions from inspiring English sources

Most disordered regions interact with protein or DNA, and may acquire ordered structure upon binding to specific proteins, DNA sequences or ligands.

The most disordered regions were eliminated using G-blocks [ 34].

Despite the abundance of these regions, the amino acid sequences of most disordered regions are poorly conserved across taxa (Daughdrill et al. 2007).

Furthermore, as seen from Fig. 5, N-site s7 is in less than 10 Å proximity to the most disordered region of the linker suggesting that this site might be critical for the quality control system in monitoring the conformational transitions in the linker region during the folding process.

These authors argued that squalene must be located in a most disordered region of the bilayer, evoking that squalene rather exists in a coiled than extended conformation and localizes to the interior of the bilayer.

Most conserved disordered regions had sequence conservation greater than or equal to that in conserved ordered regions within the same protein.

Some IDPs are either fully disordered or completely structured, but most have intrinsically disordered regions (IDRs) that comprise unstructured segments whose amino acid composition prevents autonomous folding [ 4].

It was found that mutations that cause disorder tendencies to flip to structure tendencies are the most likely mutations in disordered regions to be disease-causing [ 5].

Since a frictional ratio of 1.1 1.2 would be expected for a hydrated, spherical protein [ 40], the Sirt1 behaviour deviates substantially from that of a sphere, most probably due to disordered regions and/or a highly elongated shape.

Most of the long conserved disordered regions were in domains from eukaryotic or viral proteins [ 65].

This is one of the most accurate predictors of long disordered regions.