There is no validation data for the 3 most frequent discontinuous peptides, while discontinuous motifs ranked 4th, 6th, 11th, 12th, and 26th in the list were shown to be neutralizing.
Viewed by ranked frequencies, the top 10 most frequent discontinuous peptides covered more than 50% strains in the dataset, and top 25 discontinuous peptides covered nearly 80% of the total strain population.
These constituents are connected through their interfaces where the material displacements and tractions are most likely discontinuous, subjected to one, or more, of the five general interface conditions, i.e., perfectly bonded, dislocation-like, force-like, spring-like, and frictionless contact.
denotes the space of piecewise continuous functions with at most countable discontinuous points and at this points are right continuous.
(2) where (f:R^times R^{n}rightarrow R^{n}) is a piecewise continuous function in (tgeq0) at most with discontinuous of the first kind at the time (tau_{i}) satisfying (f t,0)=0) and (g_{i}:R^times R^{n}rightarrow R^{n}), (i=1,2,ldots) , are continuous functions satisfying (g_{i} t,0)=0).
The most frequent discontinuous peptide has coverage of 754 strains, while the second most frequent peptide covers 320 strains.
For example, the most dominant discontinuous peptides among population should be tested for neutralization assay in priority.
The top 26 most frequent (including discontinuous peptides identical to discontinuous neutralized motifs) among 402 different patterns of discontinuous peptides are listed.
