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Postural instability is one of the most disabling features in Parkinson's disease (PD), and often leads to falls that reduce mobility and functional capacity.
Poor balance control and postural instability are among the most disabling features of PD.
All or some of the components of this system may be dysfunctional in Parkinsonian patients, rendering postural instability one of the most disabling features of Parkinson's disease (PD).
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This indicates that lack of energy in itself may well not be the most disabling feature of ME/CFS.
The most prominent and disabling features in patients with mitochondrial disease are often due to neuronal dysfunction and neurodegeneration (Taylor and Turnbull, 2005).
Mitochondrial DNA diseases are a clinically heterogeneous group of multisystem disorders, with neurological deficits among the most prominent and disabling features (DiMauro and Schon, 2008).
In the milder stages of dementia, cognitive impairments are often the most disabling and distressing features for the individual and their family.
Neuronal dysfunction and neurodegeneration are the most prominent and disabling features in patients with mitochondrial disease (DiMauro and Davidzon, 2005; DiMauro and Schon, 2008).
Exertional dyspnea is the most prominent and disabling feature in idiopathic pulmonary fibrosis (IPF).
In some patients, social withdrawal or personality troubles were even the most prominent and disabling feature when the children became older.
Migraine is one of the most disabling headache disorders and the seventh most disabling disease worldwide [1].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com