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The most direct downstream targets of Rb1 were p107, NCOA2, SP1 and ATF2 (layer 3).
We show that myosin II light chain Ser19 phosphorylation, the most direct downstream event required for all types of contractility, strongly depends on proteolysis, ubiquitination and neddylation.
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Concept – The analysis of sequential change along a particular river reach following damming may provide the most direct approach for analyzing ecological impacts downstream from dams.
In conclusion, there is evidence that Gypsy-44 influences the expression level of its direct downstream gene, dmr6-like, and most likely also some genes located further downstream, possibly via impairment of the function of a CNS.
Further, we tested the role of stress-activated kinase p38 (in complex with MK-2, a direct downstream target of p38) as the most prominent mediator of stress-induced cellular senescence.
The most direct of these is trade.
Rios took the most direct responsibility.
However, the direct downstream signaling remains unknown.
It's not the most direct model.
So, we considered that Mrpl21 was not a direct downstream gene of Fir1.
Combining bioinformatics prediction and biochemical analyses, we showed that ADAM9 and ROS1 are direct downstream targets of miR-33a.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com