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And it is in Peru that the situation appears most dire, with large numbers of isolated people—Huertas estimates as many as 8000, scattered in small bands and a history of neglect.
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And it's by referencing the Hungarian-American actor Lorre, who, like Murray, could lift even the most dire movie with his mere presence, the 65-year-old actor doffs his cap to Griffiths, who has previously used Lorre in his works.
"It takes a special internal mechanism that allows somebody to walk out on that wire in the most dire of circumstances with their hair on fire and no net but with ice water in their veins and the toughness in their brain to deal with all those issues and be successful.
Though aid workers agree that the humanitarian situation in Madaya is perhaps the most dire in Syria — with children forced to eat leaves and grass to survive — civilians in Fua and Kefraya are also under duress. .
He was also confronted in January 1965 with the most dire assessment yet of America's prospects in Vietnam, delivered by two of his most influential counselors, Defense Secretary Robert McNamara and his national security adviser, McGeorge Bundy.
That does still seem rather a lot... 9.06am GMT One of the nice things about British public life is that, if you hang around for long enough, even a person with the most dire reputation can achieve rehabilitation.
They are dividing them into treatment areas for the sickest patients with the most dire injuries and using quieter corners for the growing number of patients using emergency rooms for routine medical care.
For her part, the housing commissioner, Ms. Perine, disagreed with the most dire predictions of the impact of the White House's tax proposal: that the mayor's housing plan would be completely undone.
Charities exist that help pay some of the costs, but the charities are limited in what they can do to help, and often only assist those with the most dire financial circumstances.
And amid a world of debilitating political dysfunction with the most dire potential consequences, the crucial concept of public accountability cannot and should not be narrowly confined by local or national borders, or the rigid strictures, orthodoxies, conceits and insecurities of traditional journalism.
Payments will also finance resilience-building projects in specific communities already facing the results of climate change or threatened with its most dire consequences.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com