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In the past 50 years, P. xylostella has become one of the most difficult insects to manage, primarily because of resistance evolution in some parts of the world to every class of insecticide used extensively against it [12] [14].
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According to the survey, the majority of pest control operators from Europe, Africa, Australia and North America said bed bugs were the most difficult insect pest to control, more so than ants, termites and even the formidable cockroach.
Of the >500 insecticide-resistant arthropods documented, P. xylostella ranks second in the number of cases of resistance and is considered one of the most difficult insect pests to control [ 39].
Among the most difficult plant diseases to control are those transmitted by insect vectors.
The most difficult decision.
Dinner is the most difficult.
Ms. Minor's most difficult task?
The most difficult opponent?
What was most difficult?
"That is the most difficult aspect.
It is the most difficult to achieve.
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