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The most devastating setback so far happened in the second leg of the Champions League quarter-final last spring against Manchester City.
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In January 1967, Nasa suffered one of its most devastating setbacks to that point.
The so-called "intervention" in 2007 was one of the most devastating setbacks suffered by Aboriginal people.
The so-called 'intervention' in 2007 was one of the most devastating setbacks suffered by Aboriginal people," he said in an interview in January.
But pollution is the "most devastating blow," she said.
Finally, the most devastating blow against the Bowflex Revolution is its price tag.
"Manchester by the Sea" does not present a blunt parallel with Lonergan's period of prolonged professional anguish, and it's safe to say that anyone would gladly take even the most devastating career setback over the loss that Chandler goes through.
The results marked a devastating setback for the Congress party and the Nehru-Gandhi dynasty that has led India for most of its post-independence history.
For those prisoners, Ajmi's attack was a devastating setback.
Becoming homeless was a devastating setback, but Ms. Weinu remains determined to stay on track.
It was a puzzling if not quite devastating setback for the Uncle Mo camp.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com