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Induction of skin cancer is the most deleterious effect of excessive exposure to sunlight.
The four mutations with the most deleterious effect on pVHL affinity all belonged to class 1 (L529P, A530T, P531A, Y532C; Fig. 4d, Table 2).
Its most deleterious effect was to kill off the possibility of any tall buildings in Paris for a generation: the capital essentially banned skyscrapers until last decade, though a new project by Jean Nouvel in the southeast is now underway.
The one-step addition and removal of 0.9 M Me2SO showed the most deleterious effect on rat sperm motility, plasma membrane integrity, and acrosomal integrity among the four cryoprotectants.
Thus, in this simple arithmetic task, the reduction of internal working memory capacity through articulatory suppression had its most deleterious effect on participants with higher levels of math anxiety.
From time to time, these photos crop up again to illustrate something slightly different: since caffeine has arguably the most deleterious effect on web-building of all the drugs, the lesson of the spider webs has become less about the Horrors of Drugs, and more about the surprisingly powerful psychoactive effects of caffeine.
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The SNPs with the most deleterious effects were mainly in non-HLA genes of the region, and most have not been included in GWAS arrays.
Nutritionism by and large takes the Western diet as a given, seeking to moderate its most deleterious effects by isolating the bad nutrients in it — things like fat, sugar, salt — and encouraging the public and the food industry to limit them.
"There's a good chance that it will happen in our lifetimes, before we experience the most deleterious effects of senescence," says Stolyarov.
This could link to the view that profound challenges to basic assumptions about the self, others, and the world can be one of the most deleterious effects of traumatic experience [ 4].
This could link to the view that profound challenges to basic assumptions about the self, others, and the world is one of the most deleterious effects of traumatic experience [ 1].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com