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For laboratory diagnosis, the most definitive test is virus isolation by cell culture [ 3].
Perhaps the most definitive test to determine poor outcome in post-anoxic coma is the SSEP.
The most definitive test of allele type involves placing the new allele in trans to a known null allele, but this test cannot be performed for X-linked genes.
This is perhaps the best and most definitive test to find genuine silk.
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ELD entailed up to three days of controlled removal of CSF via an implanted lumbar catheter and is considered to be among the most definitive prognostic tests for assessing shunt responsiveness [ 6].
Circumstantial evidence has accumulated for the hypothesis that many animal species practice self-medication, yet in most cases definitive tests are lacking [6], [7], [13].
The most definitive hormonal diagnostic test for 21-OHD is an ACTH-stimulation test, which measures the serum concentrations of 17 α-hydroxyprogesterone, the main substrate for 21-hidroxylase, at 0 and 60 min after ACTH administration [ 13].
Although, the definitive test (gene sequencing) is most sensitive, it is expensive and unnecessary for the vast majority of case investigations.
Visual and olfactory examination and home test kits do not offer the most definitive answers to water quality.
The only definitive test now is a brain biopsy, which is rarely done; most cases are verified only after death.
In June 2007, Shyam Sunder explained, "We are proceeding as quickly as possible while rigorously testing and evaluating a wide range of scenarios to reach the most definitive conclusion possible.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com