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In this case mTOR has become an important therapeutic target for glioblastoma (GBM) that is one of the most deadly types of cancer.
Inhibitors of such pathways are already in use for cancer therapy, with significant but as yet only partial success in the most deadly types of human cancers, against which even combinations of Ras-pathway inhibitors with classic cytotoxic drugs or irradiation are insufficient.
An urgent OVCA research priority is the discovery and validation of biomarkers useful for diagnosing the most deadly types of OVCA, which often progress rapidly [3].
Pancreatic ductal adenocarcinoma (PDAC) is among the most deadly types of malignancies because of its high ability to metastasize.
PROBLEM: Melanoma belongs to the most deadly types of skin cancers and arises from melanocytes, the pigment cells of the skin.
Evidence from the pivotal trials of anastrozole and letrozole, ATAC and BIG 1 98, has revealed important efficacy differences between these two drugs (Table 1), particularly in the prevention of early DM events, which are by far the most prevalent and the most deadly types of breast cancer recurrence events.
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MELANOMA -- The most deadly type of cancer, it begins as a small, dark, irregular mole, or as a mole that has recently changed appearance.
Over the past three decades, the incidence of melanoma, the most deadly type of skin cancer, has increased much more sharply in young women than in young men.
People who take aspirin tablets or similar painkillers on a regular basis cut their risk of developing skin cancer - including the most deadly type - malignant melanoma - by about 15%, research suggests.
In another experiment, done with mosquitoes that weren't pretreated with antibiotics, Csp_P-fed mosquitoes were given blood containing the dengue virus and Plasmodium falciparum, a single-celled parasite that causes the most deadly type of malaria.
In 2015, Beijing saw a 16percentt annual fall in the concentration of the most deadly type of air pollutant, according to an analysis by the Paulson Institute and Greenpeace of air quality data from the United States Embassy in Beijing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com