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Comparative literature assessing the relative safety and efficacy of different BoNT products is limited, most data come from reports on small samples, and only a few studies meet criteria of evidence-based medicine.
For penicillin G and flucloxacillin, most data come from observational, noncontrolled studies often in home-based care settings [45 47].
In addition, given that most data come from established research settings, the presence of a dedicated malaria research team, with improved health infrastructure and/or surveillance, is itself likely to reduce the burden of malaria that would otherwise occur in that setting.
For penicillin G and flucloxacillin, most data come from observational, noncontrolled studies often in home-based care settings [ 45- 47].
There are scarce contemporary population-based data on the incidence rate for PAD in diabetic patients as most data come from cohorts derived from hospitals.
Clinically, most data come from Phase I II studies evaluating systemic toxicity of intrapleural drug (most commonly cisplatin) administration in highly selected patients.
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Long-term studies were also uncommon, with most data coming from experiments lasting 2 3 years.
Research on the topic is incipient and most data comes from epidemiologic studies, often cross-sectional in design.
The consequences of nuclear war on the environment, like its consequences on the balance of power, were difficult to prove; most data came from computer models, and from research on other planets.
Even though most data coming from the analysis of completely sequenced genomes and directed-evolution experiments strongly support the patchwork hypothesis, we do not think that all the metabolic pathways arose in the same manner.
BACKGROUND There are limited data on morbidity and mortality in severely anemic patients for whom blood transfusion is not an option, with most data coming only from surgical patients and no data on the rate of myocardial ischemia associated with severe anemia.
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