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The most dangerous malaria parasite, Plasmodium falciparum, is an unusually versatile bug.
P. falciparum is the most dangerous malaria species as it often leads to the death and can be fatal within few hours of the first symptom [ 1].
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Along the border between Thailand and Cambodia, Plasmodium falciparum, the most dangerous of malaria parasites, is showing unmistakable signs of becoming resistant to artemisinin derivatives, the group of powerful drugs that as part of so-called artemisinin-based combination therapies have become the cornerstone of malaria treatment worldwide.
Most malaria researchers believe that the world's most dangerous mosquito a malaria-parasite-carrying species called Anopheles gambiae is a homebody that prefers biting people indoors.
24 This may, in part, stem from a lack of faith in negative rapid diagnostic test or microscopy results, a product of long held practices and beliefs that "most dangerous fever is malaria," and the fear of missing a case of malaria.
"The real problem now is that [Plasmodium] falciparum malaria is almost untreatable," Dondorp says, referring to one of the most dangerous species of malaria parasites.
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And now it has yielded an unexpected gem: The most dangerous form of malaria originated in gorillas, not chimps, as had long been believed.
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The proposed approach was evaluated on the discovery of DHFR inhibitors for Plasmodium falciparum (P. falciparum), the causative agent of the most dangerous form of malaria [12].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com