Sentence examples for most current trials from inspiring English sources

Although phase I trials of newer agents have the potential to minimise the risk of toxicity by using more rational biological end points, most current trials still use the traditional end points of toxicity for selection of the recommended phase II dose (Parulekar and Eisenhauer, 2004).

The full application and the most current trial protocol were predominately used as the main source of information, unless otherwise stated.

Most current clinical trials targeting CD19 employ CAR designs that contain the CD3-ζ with either CD28 or CD137 signaling domains.

Of course, risk calculation must always use the most current clinical trial data.

Although most current gene therapy clinical trials focus on cancer and inherited diseases, multiple studies have evaluated the efficacy of gene therapy to abrogate various forms of heart disease.

Most current gene therapy clinical trials are using viral vectors that are self-replication defective.

Most current target-driven therapeutic interventional trials will be developed according to a specific molecular profile.

Due to our very limited understanding of the principles governing tissue structure and function, most current tissue engineering typically follows a trial-and-error approach to design [ 14].

In the current setting with a reference adjuvant treatment from an RCT and very promising data from a phase-II-trial, there is the ideal basis for a controlled trial comparing the two most current and successful regimen.

In the laboratory and in current trials the siRNAs are most often chemically synthesized, bypassing the Dicer cleavage step for entry into RISC.

This review is the most current report on the topic and includes the latest published trials.