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MiR172 was selected as a loading control for all the RNA blots because it gave the most consistent signal among different tissues compared to other genes we tested, including U6.
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The strongest and most consistent signals were derived from four separate clones all related to Myc-associated zinc finger protein (MAZI: SWISSPROT Accession # P56270).
The most consistent phylogenetic signal that is seen across all data sets and types of analyses is a relationship between Cytinaceae and Malvales (Table 1).
As in KORA S4, the most consistent association signals in HYPEST were detected between rs11646213 and DBP (P = 0.017) as well as HYP (P = 0.048).
The strongest and most consistent GWAS signals have been SNPs in the 5´ untranslated region or in intron 1 associated with circulating adiponectin levels, consistent with the molecular function of adiponectin binding (GO 0055100) (Chung et al. 2011; Dastani et al. 2012; Jee et al. 2010; Morisaki et al. 2012; Wu et al. 2010).
The GFP reporter provided most consistent results with signals readily quantifiable for direct comparison of exon skipping efficiency.
The ability of muscimol to rescue the cleft palate phenotype of Gad1 and Viaat mutants suggests that multimeric GABAA receptors are downstream of Gad1 and Viaat in palate formation, a pathway that is most consistent with GABA signaling in the CNS.
The most consistent finding was increased signal on FLAIR and T2-weighted images in the periventricular and deep white matter; volumetric measurements were not available.
We found that BCL2, followed by BCL6, showed the most consistent and differential aSHM signal in FL specimens, with SNVs in 12/12 FL cases and 0/3 in the reactive LN controls.
By far the most consistent role of NDMA signalling in the PAG is its role in promoting vocalisation.
Unlike the calcium signals that emanate from synergids [ 32, 33], the proposed source of micropylar guidance signals, our results point to a diffusible, heat-labile ovule-derived signal that is sufficiently complex for rapid divergence – criteria that are most consistent with a protein-based signal.
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