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The main and most consistent risks for declining cognitive function were the baseline values of cognitive function (reflecting substantial regression to the mean), aging (a strong linear pattern of increased decline associated with greater aging, but with diminishing marginal returns), older age at baseline, dying before the end of the study period, lower education, and minority status.
In general, the main and most consistent risks for cognitive change, in descending order based on the β coefficients, were the baseline value of cognitive function, aging (the combination of the linear and nonlinear terms), age, surviving to the end of the study or being censored due to entrance into managed care plans, education (the combination of the grade school and college terms), and race.
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The most consistent risk factor for seizures at the onset or following cerebral infarction or hemorrhage is cortical involvement.
The most consistent risk factors across the different study designs, samples, and measurement methods were cognitive deficits, low treatment alliance, personality disorder, and younger age.
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First follow‐up analyses in a large collection of over 1300 AD families reveal that in addition to APOE genetic variants in ACE, CHRNB2, GAB2, and TF show the most consistent risk effects across a wide range of independent samples and study designs.
After adjustment for age, sex, neck pain at T1, and other exposure factors that had been estimated to be confounders, the most consistent risk factors were role conflict (highest OR 2.97, 99% CI: 1.29 6.74) and working with arms raised to or above shoulder level (highest OR 1.37, 99% CI: 1.05 1.78).
Moreover, increased IL-6 levels were the strongest and most consistent risk factor for cardiovascular events.
Nevertheless, the strongest, most consistent risk factors are smoking and age (Hyman and Neborsky 2002).
The most consistent risk factors were perceived stress, high work/study demands and computer use pattern.
Dementia is known as the most consistent risk factor of delirium.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com