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The most considerable challenges facing effective cancer therapy are systemic toxicity of cytotoxic drugs, their lack of tumor localizing and an even distribution throughout the whole body.
Results indicate that high capital costs for micro- generation technologies; disparity in VAT between new build and refurbishment; and the complexity of the UK existing housing stock are the most considerable LER housing design challenges.
However, technical limitations have made this a considerable challenge in most species.
Scenario 1 (the most effective scenario for both public health and environmental sustainability) represents a substantial change from the current pattern of consumption in the UK, and if it were adopted as a target, then it would be a considerable challenge for most consumers and indeed producers of food.
A considerable challenge faced by most remote rural communities across the UK is slow and unreliable broadband services.
However, most hospitals, both public and private, found this a considerable challenge (20– 20).
Since most treatments for PLP have limited effectiveness, 3 its management remains a considerable challenge.
By most accounts, users seemed pleased with the OS, but growth rates still looked to be a considerable challenge.
But a considerable challenge remains.
INTERNET start-ups represent a considerable challenge for landlords.
"Relegation presented a considerable challenge for us financially.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com