Your English writing platform
Discover LudwigSuggestions(5)
Exact(20)
Compared to the PGx variants, disease variants occur at the most conserved positions while neutral variants at less conserved ones.
The anchor residues corresponding to the most conserved positions are N1.50, D2.50, R3.50, W4.50, P5.50, P6.50 and P7.50 (Ballesteros' numbering [22]).
The most conserved positions are mainly located in the active site cleft, and the intermediately conserved positions are clustered in other functionally important regions.
The varying number of cationic charges in S4 segments of the various domains of rNav1.4, from five to eight (Fig. 5) might not interfere with residue interactions if the 2nd, 3rd, 4th, 5th, and, to a lesser extent, 6th cationic sites are those primarily involved in gating since these are the most conserved positions.
We call all these most conserved positions "locked" because they "can't escape" by freely mutating.
Canonical splicing dinucleotides are the most conserved positions in splice sites (GT/AG).
Similar(38)
The most conserved position in each transmembrane helix n (TMn) is numbered n.50 and is used as a relative reference.
It would be interesting to know whether the most conserved position in dif XerC (position 5) is associated with a conserved amino acid residue in XerC.
However, the two most conserved motif positions in plastids coincide with the two conserved positions in experimentally characterized sites upstream cysPTWAM, cysK, cysJIH, cysDNC, sbp, and cysB in proteobacteria.
The most conserved informative positions supporting a clade are binary, i.e. with two character states only.
Besides the matrix score, they define a core region, which is usually the first 4 5 most conserved consecutive positions of the matrix, and perform the core score threshold check.
More suggestions(15)
most conserved molecules
most conserved enzymes
most conserved proteins
most conserved regions
most conserved spacers
most conserved caspases
most conserved motifs
most conserved aspects
most conserved residues
most conserved sequences
most powerful positions
most supervised positions
most demanding positions
most susceptible positions
most uncomfortable positions
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com