Calmodulin (CaM) is one of the most highly conserved molecules.
DNA is the most evolutionarily conserved molecule.
Most miRNA studies utilize evolutionarily conserved molecules that readily enable studies in vivo in experimentally tractable animals such as rodents.
Toll-like receptors (TLRs) are a group of highly conserved molecules that allow the immune system to sense molecules that are present in most classes of pathogens.
Hsp60 are highly conserved molecules inducible by all forms of cellular stress.
They are receptors for structurally conserved molecules derived from microbes.
The biogenesis of these evolutionary highly conserved molecules is carried out in a multistep process.
Toll-like receptors (TLRs) function in innate immunity by recognising structurally conserved molecules on microbes.
The rationale behind this is that GroEL is a highly conserved molecule and most of the sites involved in ATP binding or GroES and substrates binding are very conserved as to be detected by conventional coevolutionary analyses.
Perhaps this reflects the key role of this highly conserved molecule for cardiac function [ 17].
