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ESCRT-III and the Vps4 complex are the most conserved building blocks of the ESCRT machinery.
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To scrutinize the evolutionary relationship of the pseudomonad tailocins with these prophages, as well as with related sequenced phages, we focused on their most conserved proteins: Ptb proteins equivalent to the phage P2 proteins building the tail spike (PtbD, GpV), tail sheath (PtbJ, GpFI), tail tube (PtbK, GpFII), baseplate hub (PtbQ, GpD), and baseplate (PtbE PtbF, GpW GpJ).
Again, the higher one is selected for this building block to represent the similarity of the most conserved part.
Overall, PmoA is by far the most conserved subunit of this enzyme.
As shown in Fig. 2, this HTH motif possesses the most conserved amino acids residues.
The importance value index of A. mexicanum was greater in the most conserved landscape.
Glycolysis, the breakdown of glucose, is one of the most conserved and extensively studied biochemical pathways.
The non-structural protein 5 (NS5) of flaviviruses is the most conserved amongst the viral proteins.
SufC, a cytoplasmic ABC-ATPase, is one of the most conserved Suf proteins.
These were targeted against the most conserved second exon of HIV-1 TAT/Rev/Env region.
However, some sequence divergence has been observed even within the most conserved regions of the viral genome.
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