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Strikingly, the region most conserved between mouse and human NEAT1 is also the most conserved region between human NEAT1 and NEAT1 of dogs, rats, and cows (data not shown).
We analyzed cis-SNPs in regions that were most conserved between the mouse and human genomes.
At the protein-protein interaction level, interactions involved in "Cell cycle" and "Metabolism" were the most conserved between the two datasets.
The region most conserved between PNPs from different plant species has also been shown to be the key to its physiological activity [ 13].
Importantly, it has been reported that succeeded HGT events between distantly related bacteria mostly implicate housekeeping genes that are also the most conserved between different species [ 35, 36].
Three regions including the N-terminal ends were found to be most conserved between the PSI-BLAST alignments; these three regions were aligned separately by Clustal W (Fig. 3).
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Only between human and chimpanzee most of TFBS are conserved.
The eIF4E-1d is the next most conserved, with 70% identity between the two species.
N-terminal and C-terminal domains were the most divergent between taxa and the first and second intracellular domains were the most conserved of the non-transmembrane domains.
Analyses confirmed the close genetic relationship between Norwegian and Scottish ISAV and indicated that this segment was among the most conserved of the ISAV genes identified to date.
The P-Loop, Kin-2A and GLPL motifs were most highly conserved between all species examined, while the RNBS-I and RNBS-II motifs were conserved within the Poaceae, and the Kin-2A and RNBS-II motifs were the most conserved among the CC-NBS sequences.
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