Exact(2)
In the third and most conservative hypothesis only the compliant are considered covered, so all non-respondents who were not compliant to screening are considered not covered.
The coverage among screening compliant was 92.4%, among non-compliant 69.0%; after adjusting for screening compliance the predicted coverage among non-respondents was 74.6% and 82.4% in the general population; according to the most conservative hypothesis, i.e. none of the non compliant who did not respond were covered, the estimate is 66.0% (figure 2).
Similar(58)
While this assumption does seemingly provide the most conservative approach, alternative hypotheses, such as apoptosis, could lead to different conclusions regarding hepatocyte loss.
Our approach presented above represents the most conservative procedure consistent with our hypothesis, because it allows each gene to add at most one connection to another gene in the inferred network.
The sample size estimate of n = 350 participants is based on H2, the non-inferiority hypothesis, as this is the most conservative [ 49, 57, 58], and on a randomization of three experimental groups in a 2 2 1 ratio [ 59].
The most conservative (in this case – overestimating) linear no-threshold hypothesis was used to calculate excess cancer expectations for cleanup workers, the population of the contaminated areas and the global population.
The most conservative (in this case – overestimating) linear no-threshold hypothesis (LNTH) of radiation carcinogenesis was used to predict excess cancer expectations for cleanup workers, population of the contaminated areas and global population.
On the basis of the most conservative assumption of a 30% survival rate at 1 year (null hypothesis) in historic controls with locally advanced pancreatic cancer (Okusaka et al, 2004), an increase of 50% or more (alternative hypothesis) could be shown with a power of 80% by investigating a sample size of at least 35 patients (α=0.05, one-sided test) (A'Hern, 2001).
This is intermediate between using a raw p value (least conservative) and Bonferroni correction (most conservative), and accounts for the fact that many of the genotypes are in partial LD and, thus, many of the hypothesis tests are correlated.
Its most conservative counterpart has followed suit.
The most conservative people are the students.
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