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Participants lost to follow-up will be considered non-abstinent the most conon-abstinent thetion.
First, under the most conservative assumption (i.e., assuming the smallest decrease in water use in response to a financial incentive), using projections from Abu Qdais and Al Nassay [8], per capita consumption decreases by a relatively small amount: from 544 to 500 l/c/day.
Those lost to follow up will be modelled in various ways including having continued to smoke (the most conservative assumption).
The most conservative assumption is a MCID of 1 with an SD 2. We will have 89% power to detect this MCID.
Later, in multivariable-adjusted analyses, we re-coded these data as the absence of the risk factor to make the most conservative assumption.
In calculating the required sample size, we therefore made the most conservative assumption of a response rate of 50% for the design factor under investigation and a response rate of 40% for the comparison design factor.
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So even under the most conservative assumptions, returns from here are not at all bad.
However, we considered it more suitable to use the most conservative assumptions.
This near-optimal performance is invariant under various assumptions about how the reward rate is computed, and is, even under the most conservative assumptions, in the range of 90% of the optimal reward rate.
We conducted our statistical analysis for this publication with Stata V.9.1 and 11. 37 Descriptive statistics (eg, means, proportions and CIs) were produced by the Stata survey/panel data methods with the most conservative assumptions (eg, finite-population assumption, linearised proportions and binomial Wald statistics for CI of proportions).
The results of the sponsor's de novo model led the sponsor to conclude that even with the most conservative assumptions, the MAGEC system is cost saving, compared with conventional growth rods, and cost savings are usually realised during the third year following insertion.
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