Under this model, the most cost-effective strategy for fine mapping would focus on assaying coding variation, which can most comprehensively be achieved through whole-exome re-sequencing of cases and controls, and will provide a complete catalogue of protein altering variants across the genome.
While these decades of study might suggest that the supply of Streptomyces natural products is nearing exhaustion, in fact, genome sequencing efforts have revealed that the well is far from dry, even in the most comprehensively studied strains.
The CTD contains approx. 50 repeats (depending on the species) of the consensus sequence YSTPSPS and can be phosphorylated on multiple residues, with Ser and Ser phosphorylation being the most comprehensively characterized [ 53, 54].
Claim 2: "Nothing was more laughable than the sequence showing a huge poster of the infamous 'hockey stick' temperature graph being driven round London on the back of a lorry, without any mention of the expert studies which have made the 'hockey stick' one of the most comprehensively discredited artefacts in the history of science".
Probably pound for pound, he's the most comprehensively talented film-maker I've worked with.
She concludes by describing how philosophy most comprehensively embodies the secular craving for knowledge of the real.
It is the most comprehensively planned new town since Columbia, Maryland, and Reston, Virginia, were built, in the mid-'60s.
There is nothing more boring than referee-bashing, as has been most comprehensively proved in football this weekend.
The xylanases of GH10 and GH11 families have been studied most comprehensively (Motta et al. 2013).
PTPs are, from a structural biology viewpoint, one of the most comprehensively covered protein families.
