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Exact(6)
Ion suppression due to the matrix was <20% for most compounds, and higher than 60% for EME and diethylpropion.
The 3-parameter sink diffusion model provided acceptable fits for most compounds and the 4-parameter two-sink model provided acceptable fits for the others.
For both fibers, the method was linear in a range of 2 orders of magnitude, giving relative standard deviation (RS D) below 10% for most compounds and detection limits at the low pg/mL level.
Gonon and co-workers found that electrochemical pretreatment of carbon-fiber microelectrodes dramatically altered the voltammetric characteristics of most compounds and enabled their resolution.
Measured solubility data (see Supporting Information) were available for most compounds and were generally within acceptable levels; this might have been expected given the distribution of lipophilicity and aromatic rings.
MICs correlate poorly with the in vivo efficacies of antimicrobial drugs in patients with B. quintana infection, and this discrepancy may be explained by the lack of bactericidal effect of most compounds and by sequestration of the bacterium in erythrocytes (40 ).
Similar(54)
The IC50 values ranged from 0.021±0.003 (pemetrexed in MSTO-211H cells) to 14.59±4.58 μ (sorafenib in H2452 cells), and most compounds (gefitinib, erlotinib, enzastaurin and ZM447439) displayed similar growth inhibitory activities in these tumour cell lines.
Some xenoestrogen effects were seen at the 10 pM concentrations for most compounds; OP, NP and BPA all decreased mERα, and PP decreased mERβ.
The results primarily illustrated kinase promiscuity: 60% of the kinases interacted with 10-40% of the compounds and most compounds had interactions with kinases from multiple groups, which was in line with the analysis by Bamborough et al.[21].[21]
These VOCs have widespread applications and multiple uses, and most compounds were detected throughout the conterminous United States and in Alaska.
It excludes control measurements altogether under the assumption that most compounds are inactive and can serve as intrinsic controls.
Related(20)
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