Sentence examples for most complex traits from inspiring English sources

Exact(47)

After all, for most complex traits, the question is not whether there are genes, only when and how they might be found.

For most complex traits we have a poor understanding of the positions, phenotypic effects, and population frequencies of the underlying genetic variants contributing to their variation.

Crop yield is one of the most complex traits.

Human geneticists increasingly appreciate that most complex traits that have a genetic component are influenced not by just a single locus, but by complicated gene-gene interactions [64].

In the latter case, ∼50% of the negative trait heterosis under additivity does not appear to fit the observed heterosis for most complex traits, particularly fitness and its components.

Consequently, current GWAS of most complex traits only have identified a small fraction of trait variance (5 to 10%), leaving much of the heritability of these traits unexplained [6].

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Like most complex trait loci, these OA loci are thought to influence disease susceptibility through the regulation of gene expression, so-called expression quantitative loci, or eQTLs.

A second reason for the limited application of GWAS findings to medical care is the low predictive accuracy achieved by current genomic predictors of most complex human traits, including highly heritable traits such as height (9– 11).

It is too early to say which viewpoint will be appropriate for most common complex traits, although an epistatic model might be judged rather more plausible in most cases and this would favour the more sceptical view.

The treatment given in this paper illustrates how it is possible that even the most complex organic traits might be explained in terms of the slow, steady action of simple laws (natural selection) upon the system's most basic components (genes).

However, this is unlikely to be a serious problem for most complex disease traits.

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