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In most complex diseases, much of the heritability remains unaccounted for by common variants.
Prestigious journal molded a field of elegance that has failed, however, to produce tangible results as most complex diseases are still uncured [14, 15].
As an application, we apply the approach to HIV/AIDS treatment planning, a technical challenge since AIDS is one of the most complex diseases to treat.
Like many common diseases, MS has a genetic component; however, as with most complex diseases, the genetic architecture may be influenced by heterogeneity, incomplete penetrance, polygenic inheritance, and environmental factors.
Typical of most complex diseases, asthma susceptibility appears to be multifactorial, including contributions by several genes and multiple environmental factors.
We believe that for most complex diseases, the Vg of susceptibility variants are likely to be rather small.
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Those disparate responses, coming one month apart, illustrate how much the C.D.C. is learning -- and how much it had to learn -- in trying to manage what may be the most complex disease outbreak in its history.
F1 The Biological Threat THE C.D.C. -- In trying to manage what may be the most complex disease outbreak in its history, the Centers for Disease Control and Prevention has drawn praise for devising a treatment plan that has greatly reduced the fatality rate from inhalation anthrax.
Most complex disease genes are those that originated during the emergence of vertebrates.
However, this is unlikely to be a serious problem for most complex disease traits.
Most complex disease genetic studies, including many in IBD, have been beset by poor reproducibility of results and slow progress in identifying disease genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com