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These preformed and most compatible conformations are conformations at local minima of their potential energy surfaces (local minimum conformations).
When the most compatible conformations of both partners are most prevalent, the conformation selection theory becomes the lock key theory [1].
Alternatively, the conformation selection theory describes that both guest and host select their preformed conformations that are most compatible with one another to effect binding by shifting two equilibriums progressively from less compatible to most compatible conformations for both partners [2] [5].
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Molecular complexation in biology is best described by the conformational induction theory [1] namely, a guest binds initially to a less compatible conformation of its host and then adjusts its conformation to induce the most compatible conformation of the host.
Molecular complexation in biology is best described by the conformational induction theory [1] namely, a ligand (e.g., a small molecule) binds initially to a less compatible conformation of a receptor (e.g., a protein) and then adjusts its conformation to induce the most compatible conformation of the receptor.
and most compatible systems.
Most compatible cities.
This filtering step yields 730 drugs most compatible with virtual docking (Table S7).
Gene duplication in a protocyanobacterium is the alternative most compatible with present data.
Know your most compatible matches.
Dog: most compatible with tiger, rabbit, horse; least compatible with ox, dragon, sheep, rooster.
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