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As far as we are aware of, this is the most compact gene set capable of classifying the largest number of tissues.
Compared with the previous studies, the two-way clustering algorithm applied in this study appears more efficient in finding the most compact gene subsets that have achieved an improved prognostic accuracy over the DLBCL patients' survival profiles.
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Vertebrate mitochondrial genomes are among the most compact, gene-rich genomes, while some plant mitochondria have evolved to have a low percentage of coding region similar to that of nuclear DNA [ 2].
The most compact paralogous gene set appeared to be the one including [TSHβ].
The most compact paralogous gene set was the [GPA2]-containing one and was condensed into 6 Mb of human chr.
T. rubripes has the most compact genome, which contains only two Arp genes encoding Arp3 and Arp5, so far the smallest number of actin-related proteins in a sequenced genome (Table 6).
The most compact genome (A. terreus), contains only the core set of mitochondrial genes, while other genomes contain at least one accessory gene.
The researchers hope to learn from such primitive Cas proteins, which are the essential components of the Cas enzyme, so that they can design the most compact and sleek gene cutters they can.
In this study, we applied an integrative approach that combines a SPC-based two-way clustering with a functional consensus metric to identify functionally sounding and the most compact subset of genes underlying the phenotypic partitions of patients.
Among free-living taxa, Ostreococcus species also contain the most compact (i.e., gene-dense) genomes [3].
Furthermore, deletional bias, rather than natural selection, is the primary mechanism by which the compact gene packing within most prokaryotic genomes is maintained.
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