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Furthermore, the 20q13 region has been reported as the most commonly amplified region in cancer and 13 of the amplified genes were proposed as "cancer initiating genes" [ 38].
Among seven TDRDs that had the highest frequency (>10%) of gene amplification, the plant homeodomain finger protein 20-like 1 (PHF20L1) was the most commonly amplified (17.62%) TDRD gene in TCGA breast cancers.
The most commonly amplified genes were HAPLN1 CRTL1), ADAM29, SMAD2, and SMAD4 (Table 3).
The most commonly amplified single region (18/23 cases; 78%) corresponded to a region localized at chromosome 20q11.22 identified by the SNP_A-2220183 and the SNP_A-2039695 at the 33,776,127 bp and 33,954,944 bp positions, respectively (Table S1).
The FGFR1 gene is one of the most commonly amplified genes in cancer [ 39].
The genes most commonly amplified by researchers are gltA and ompB; followed by the 17-kDa gene.
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Random hexamers, the most commonly employed, amplify only fraction of the transcriptome, comparing with random pentadecamers [ 10].
The most common of these, 1q23, spanned a 5.4 Mb region with a commonly amplified segment of 0.8 Mb.
The magnitude of that movement is commonly amplified electrically.
Out of 669 culture collection samples from 11 collections, we retrieved 566 COI amplicons as some taxa failed to amplify (most commonly, these were Amphidinium sp., Heterocapsa sp., Oxyrrhis sp. and some unknown gymnodinioid dinoflagellates).
Far from promoting safety, the most commonly cited justification, solitary confinement often amplifies violent impulses, turning prisoners into ticking time bombs who are far more dangerous to human society upon release than they ever were to begin with (see National Geographic's documentary on the subject, available on Netflix).
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