Notably, the most common toxicity was observed in hematologic compartment, suggesting a more potent toxic effect on hematologic malignancies.
In dogs that received repetitive weekly doses, the most common toxicity (n = 9) was a grade 3 hypersensitivity reaction during intravenous administration; six dogs out of 14 (42%) had more than one clinical episode (i.e., vomiting, hypotension, and tachycardia) that was not prevented by pre-medication (famotidine, diphenhydramine and dexamethasone).
The most common toxicity was anemia (26.2%).
Mucositis was the most common toxicity.
The most common toxicity was cough (60.9%, 14 patients).
In non-CRC patients, fatigue was the most common toxicity.
The most common toxicity was haematological, mainly granulocytopenia.
Myelosuppression, manifested typically as neutropenia, was the most common toxicity.
The most common toxicity was drowsiness grades 1 2.
The most common toxicity is from chloride in the irrigation water.
As is seen with 5-Aza, myelosuppression was the most common toxicity.
