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The most common surrogate is Mn2+ that can replace magnesium in the majority of enzymes where ATP-Mg is used as a substrate [ 5].
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The most common surrogates were children (47%), followed by husbands (27%).
However, plasma drug concentration (which is the most common effective concentration surrogate) can be imperfect as it may vary from that in the tissues.
Second, most studies in this review used common surrogate outcome measures, such as prescribing rates or proportions of patients achieving specific medication use practices.
The most common statement was the belief that a surrogate is always immediately available (n = 15).
It was an example of Bradbury's most common theme, the loss of humanity through, in this case, a surrogate for parenting, as embodied by a sort of mega-TV.
In both groups, drug interventions (surrogate: 58%; final: 61%, P=0.33) and not for profit sponsorship (surrogate: 58%; final: 56%, P=0.86) were most common.
The most common concern, reported at eight facilities, was that providers failed to assign a surrogate altogether.
Dual energy X-ray absorptiometry (DXA) is the most common clinical tool used to measure areal bone mineral density (aBMD), an accepted surrogate for bone strength.
35 Determination of serum ALT is the most common test used for identification of patients suffering from liver disease, and also acts as a surrogate marker for disease severity and/or an index of hepatic activity.
Our goal was to determine miRNA activity in some of the most common sarcoma subtypes with a recently developed algorithm which uses sarcoma gene expression data as a surrogate.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com