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Researchers hope it will directly combat the most common mutations of a protein that malfunctions in cystic fibrosis patients.
New drugs capable of restoring the CFTR protein damaged by the most common mutations are required.
The most common mutations disrupt the movement of C.F.T.R. from its point of origin to its site of operation and cause a severe and ultimately fatal disease.
23andMe offers limited medical testing — for example, looking for three of the most common mutations in breast cancer genes that occur mostly in Ashkenazi Jews.
The highly "recurrent" mutations — occurring in the tumors of many people — may be the most common mutations in melanoma cells found to date.
Traditional carrier screening assays are designed to look for only the most common mutations within a gene owing to cost considerations.
Activating mutations in the luteinizing hormone receptor (LHR) gene are one of the most common mutations found in the gonadotropin receptor genes.
The most common mutations in acute myeloid leukemia (AML) are those that cause the activation of FMS-like tyrosine kinase 3 (FLT3).
It is based on annealing of two hemi-probes into its complementary sequence and was designed to detect the 33 most common mutations in RYR1 gene.
The oxidation of guanine by free radicals leads to G-T transversion, one of the most common mutations in human cancer.
The most common mutations observed after nevirapine treatment are Y181C and K103N, which are also observed with other NNRTIs [4].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com