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"most common malady" is correct and usable in written English.
You could use it to describe a widespread problem or issue. For example: "Poverty is the most common malady in many parts of the world."
Exact(3)
She would not say how many iPhones the shop had repaired, but she did say that cracked screens were the most common malady.
According to Mother Jones, Sydenham once declared that female hysteria -- which he attributed to "irregular motions of the animal spirits," was the second most common malady of the time, just behind fevers.
Otitis media (OM) is the most common malady for which children receive medical and surgical attention in the United States and Europe [1].
Similar(54)
And her filmmaking can suffer from one of the most common maladies of really famous celebrities in the world making movies: a lack of outside oxygen, or opinions.
Autoimmune diseases are some of the most common yet least understood maladies in medicine today.
The most common human form of this malady, called sporadic Creutzfeldt-Jakob disease or C.J.D., seems to arise spontaneously in the brains of about one per one million people.
Most of us suffer from this same common malady.
When functioning correctly, the immune system continually protects us from the most common to the most deadly and mysterious maladies: common influenza to HIV and cancer.
Surveys by Relate, a relationship-support charity, have found that various psychic maladies, such as loneliness and concern about work-life balance, are most common between 35 and 44.
He is infected with a common malady — nostalgia without memory.
Sinus squeeze is a common malady of persons flying in unpressurized aircraft and of divers.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com