TREG purified from healthy donors with the two most common haplotypes showed similar capacity to inhibit heterologous effector T cells.
In another word, IgG2b IgG2c IgG2a haplotype proposed by Morgado et al. (1989) may exist in some strains of mice, but IgG2b IgG2a and IgG2b IgG2c are likely to be most common haplotypes in mice.
The two most common haplotypes were GCGT (lung cancer: 58.6%, control: 64.7%) and CCGG (case: 23.8%, control: 26.1%) (Table 4).
Many studies demonstrated that haplotype diversity can be reduced to a smaller set of "haplotype-tagging" SNPs (htSNPs) identifying the most common haplotypes [42], [43].
Several algorithms have been developed to identify a minimal subset of htSNPs that can characterize the most common haplotypes [16] [18].
Several algorithms have been developed to identify a minimal subset of SNPs, i.e., tagging SNPs, that can characterize the most common haplotypes [41].
Estimated frequencies of the five most common haplotypes and their associations with CAD with respect to the presence of T2DM are shown in table 5.
MSP1 vaccine haplotypes grouped with three distinct subgroups of the four defined (Figure 2 P; Figure S3 F), each representing the most common haplotypes.
Among all eligible births for the study, the most common haplotypes were HHA, HHD, HHE, and HHF2, with allelic frequencies of 0.44, 0.34, 0.29 and 0.34, respectively.
Most of the remaining moths shared a third common haplotype, but again this was relatively divergent compared with the two most common haplotypes.
With relatively fewer known females available for sampling, the most common haplotypes increase in frequency, typically missing rare or infrequent haplotypes in sampling events.
