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In addition, epigenetic alterations are the most common genome changes in prostate cancer cells and are associated with defects in gene function, contributing to carcinogenesis and helping the cancer cells survive and grow under androgen-independent conditions.
Our genome-wide genotyped data, ready for analysis after quality control (QC), comprises information for 518,245 markers in 5732 individuals of different ethnic backgrounds, which is available in the most common genome builds (i.e. 36 and 37).
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A group of indels whose exact sequences (including the indel and ± 18 bp of the flanking sequence) were unique to their genome location were the most common ("genome-unique," 92.3%), followed by the group of indels with copies present elsewhere, but exclusively on chromosome 22 ("chromosome-unique," 7.2%).
The most common mitochondrial genome is NB, which is present in the B73 line.
Studies have shown that glutathione-s-transferase π (glutathione-s-transferase πation is the most common somatic glutathione-s-transferase πostate cancer development (Lee et al, 1994; GSTP1l, 2000; Kang et al, 2004).
The most common gene found in 304 genomes is alpha-glucosidase (Type 1), which hydrolyzes disaccharides and is usually involved in the endmost step of polysaccharide catabolism.
Long terminal repeat (LTR) retrotransposons are most common in plant genomes while animal genomes, including the human genome, are often flooded by non-LTR retrotransposons.
Polymorphisms distributed among polyphyletic sets of strains was the most common pattern of genome alteration observed, indicating that strain-specific genome variability is significant.
b For most common USS in genome only.
Multiple displacement amplification (MDA) is the most common method for genome amplification for sequencing purposes as MDA generate relatively long amplification products (majority between 5-20 kb) [ 17].
Previous comparative mapping studies across solanaceous species have revealed that inversions have been the most common cause of genome rearrangements--with translocations occurring at a lower frequency.
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