Sentence examples for most common constitutive from inspiring English sources

Expression builder aligns probeset genomic coordinates to Ensembl genes and exons along with probeset to transcript associations from the Affymetrix probeset annotation file (HuEx-1_0-st-v2.na23.hg18.probeset.csv) to identify probesets that are most common (constitutive) to all transcripts for an Ensembl gene.

The most common constitutive promoter used for gene expression in Streptomyces is ermE*p (37).

The most common BRAF mutation (BRAF V600E) leads to constitutive activation of the mitogen-activated protein kinase (MAPK) pathway.

Uniaxial tensile testing is a most common way of obtaining the information about the constitutive behavior of a material during gas forming.

As in the case of meaning, the most common idea on the market is that the rules constitutive of content are rules that subjects having contentful mental states need to follow.

Constitutive activation of the PI3K pathway is among the most common events in human cancer, and the downstream kinase mTOR restricts autophagy in response to starvation [ 23, 24].

The most common oncogenic BRAF mutation in melanomas, V600E (formerly called V599E), results in constitutive ERK signalling in vivo and can transform immortal fibroblasts (Davies et al, 2002) and immortal mouse melanocytes (Wellbrock et al, 2004).

Mutations leading to constitutive activation of the PI3K/Akt/mTOR signaling axis are among the most common found in human tumors.

For example, constitutive pro-inflammatory TAM activation is a feature of the most common human sarcoma, gastrointestinal stromal tumor (GIST), and these TAMs constrain tumor growth.

In total, mutations that result in a V600E substitution in BRAF and consequent constitutive activation occur in approximately 45% of PTCs in adults, making BRAF mutations the most common defined genetic abnormality in thyroid cancers (Xing, 2005).

The most common K-Ras mutations are in the form of point mutations on exons 12 and 13, typically resulting in constitutive activation of RAS [ 13].