In cases where microarray data from more than one probe was reported, the data which matched the RT-qPCR data most closely was used.
A1C performs well as a diagnostic tool when diabetes definitions that most closely resemble those used in clinical practice are used as the "gold standard".
We will test our hypotheses in two models, the first using data from a well-characterized, narrowly defined set of subjects selected to most closely resemble those used in the original study by [ 15] (young adults with no prior history of depression), and a more broadly defined group of subjects.
The mean of the two measurements most closely aligned is used for analyses.
This strategy was also considered to most closely parallel that used to characterize the GI morphology, to examine the GI cells most likely to express pCREB and to capture unanticipated gene expression changes.
First developed for yeast genomes [ 90, 91], some of which are intron-rich, the Amadea workflow has been implemented to take into account the intron pattern [ 92] of the most closely related species used as a reference.
When comparing all three methods, the two maximum likelihood approaches agree most closely, suggesting that using parsimony may indeed have an impact on inferred substitution histories.
The mean of the two most closely aligned measurements is used to calculate BMI (weight (kg)/height (m).
One report that most closely approximated our methodology used the higher resolution 500K Mapping array set and Affymetrix U133A and B arrays to monitor gene expression [ 6].
Without well-preserved, complete specimens, it is hard to tell who is most closely related to whom using cladistics.
