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Most clinical research evaluates diagnostic tests by accuracy measures such as sensitivity and specificity.
Forty years ago, when most clinical research took place in academic settings, the main dangers to research subjects came in service to genuine scientific aims.
Adequately representing and integrating temporal data and domain knowledge is difficult with the database technologies used in most clinical research systems.
One reason trauma research has languished, scientists say, is that the Defense Department, the institution with perhaps the biggest interest in improving care for sudden, serious injuries, was long prohibited by law from participating in most clinical research in trauma or financing it.
Most clinical research is carried out at hospitals run by medical schools.
Thirdly, practices of residual use of human tissue and data procured in the context of healthcare often do not directly fall under the remit of most clinical research legislation.
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Most clinical researches show that 44% of the patients diagnosed as cognitive impairment turn into Alzheimer's transit (AD) within 3 years in follow-up studies at an annual average rate of 15% [1].
While the principles have since been adopted by most major clinical research studies and for use in most low vision clinics, use of charts of this design and application of letter-by-letter scoring are also important for the accurate assessment of visual acuity in any clinical setting.
Nevertheless, we believe we chose the most typical clinical research situation, making our model relevant to most ethicists and clinical scientists.
MSI analysis with the NCI-panel of five microsatellite markers (2 mono- and 3 di-nucleotide repeats) still appears to be a preferred method in most clinical and research laboratories.
However, the benefit of exact determination of the concentrations of C20 0, C22 0, and C24 0 seems small for most clinical and research applications, which must be weighed against the loss of productivity and the increasing risk of FA degradation or isomerization during derivatization [24] [26].
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