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MFE-23, the most characterised of these sFvs, is reactive with carcinoembryonic antigen (CEA), a glycoprotein that is highly expressed in colorectal adenocarcinomas.
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One of the most well characterised of these G proteins is mammalian Arf6, a protein that participates in many cellular processes including endocytosis, actin remodelling and cell adhesion.
A number of the NLRs are known to form inflammasomes, but physiologically relevant roles have so far only been shown for those formed by NLRP1, NLRP3, NLRC4 and NAIP5, the most well characterised of which is NLRP3.
Haematopoietic stem cell (HSCs) are among the most well characterised of somatic stem cells and have served as a paradigm for stem cells in other tissues, with the notion that maintenance of quiescence is critical for somatic stem cell function being largely derived from studies of HSCs.
The complex is the most upstream component so far characterised of the environmental arm of the general stress response in B. subtilis[ 1, 4].
Alex Clark writes: You could argue that Muriel Spark's body of work was most effectively characterised as the study of charisma and the deceptions that can be carried out, almost unstoppably, under its auspices.
Known functional sites are for the most part characterised by solving structures of proteins in complex with their partners.
Their occurrence has been most extensively characterised at the telomeric ends of eukaryotic chromosomes, whose DNA comprises such sequences, and where the extreme 3′ ends are single-stranded.
In type 1 diabetes, absent pancreatic insulin secretion is the opposite phenotype to the endogenous hyperinsulinaemia characteristic of most conditions characterised by insulin resistance.
There's no sense of how these blustering, thrusting men might themselves be perceived as disruptive, and no attempt to understand the women's tactics as a form of self-preservation: even Chiku, the most attentively characterised of the three, emerges as a spoilt princess whose actions are presented as first questionable, then actively hateful.
Most samples characterised by an elevated expression for the first metagene were also characterised by an overexpression of EGFR and/or ErbB2 as shown in Figure 4B.
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