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Matching the skills and qualifications of a candidate to your list of priorities is most challenging when you're counting on the person to shake up the dynamics of the position.
This undoubtedly challenging task involves considering structure activity relationships that govern the interaction of the starting molecules with their specific targets, and becomes most challenging when these targets are only slightly related or unrelated (i.e. when they belong to different protein families) [32].
Some studies indicate this is most challenging when they are from low-income groups [ 42, 45, 50], although cost of food was not as salient for our participants.
In our experience, these unusual features are most challenging when PA occurs in the supratentorial compartment, especially in adult patients, a group of patients and a location which would not readily prompt consideration of PA but rather of diffuse glioma.
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I have highlighted the significance of this trend line in previous weeks by noting that the market has faced its most challenging times when the VIX is trending above this moving average, and has experienced strength when below this all-important trend line.
In the most challenging moments, when we faced the most difficult issues -- of war and peace, of whether to take on some powerful interest -- he was always there.
To me, some of the best moments have been some of our lowest moments, our most challenging moments, when I've seen him deal with them with such poise and calm and focus.
Mr. Clinton, who has said Mr. Gore's election is crucial to protecting his own legacy, offered this testament: "In the most challenging moments, when we faced the most difficult issues of war and peace, of whether to take on some powerful special interests, he was always there".
Finally, as discussed by Han et al. in [7], the 'parallax' is perhaps the most challenging problem when it comes to image registration.
Among the most challenging concerns when imparting shared values like accountability, transparency, liberty, fairness and trust into information technology are reliable and comprehensive formal and computational models of those values.
Determination of the optical constants n and k, is one of the most challenging tasks when studying the optical properties of materials since this involves complex equations and a great deal of computing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com