In gastric surgery, the area of the suprapancreas is one of the most challenging sites; we perform lymph node dissection strictly and carefully because of its various anatomical variants of the vessels.
Monique Gerbex, a work order scheduler from Wolcott, Vt., will be scheduling maintenance work in unfinished parts of the new station -- perhaps the most challenging building site on earth, where work never stops and ingenuity is a job requirement.
Photograph: Rodrigo Abd/AP 11.41am GMT One of the Crossrail tunnels under construction 35m below the streets of Whitechapel, east London, which has proved to be one of the most challenging and impressive sites in the whole Crossrail project.
In a 2012 report, the National Research Council called Redstone "the largest and most challenging" of the buried chemical weapons sites.
A charity that works with the government on the free-school project, the New Schools Network, said finding a site was often the most challenging aspect of setting them up.
The Renaissance Society, affiliated with the University of Chicago, specializes in "this country's most challenging and provocative art," according to its Web site.
It doesn't get more exclusive than Pine Valley Golf Club, rated by Golf Digest, dozens of Web sites and boldface names by the bushel as the most challenging course in the world.
The most challenging of the current ventures is the $20 million redevelopment of the 1903 Goodwin Estate, a National Historic site in Hartford's West End, home to high government officials and professionals.
Such procedures are most challenging, since functional recovery is slow, and often unsatisfactory results occur with the inherent morbidity of the donor site.
