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Lungs are known to be one of the most challenging organs in MRI.
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Among these sites, bone is the most challenging organ for therapeutic intervention as bone metastasis can cause severe skeleton-related diseases such as bone pain, hypercalcemia, fractures and nerve compression syndromes (Saad et al, 2006; Sturge et al, 2011).
Mild hypothermia represents one of the most challenging aspects of prevention of organ failure [ 53], since it can improve outcome but may also be associated with marked side effects [ 54, 55].
Patients with multiple organ failure (MOF) are the most challenging group of patients in modern intensive care.
One of the most challenging aspects of spastin-related pathogenesis is that, despite its ubiquitous presence in many different organs, mutations of this protein result in the specific degeneration of processes of long-range projection neurons.
Along with patients on extracorporeal membrane oxygenation [ 2] or those with augmented renal clearance [ 3] or rapidly changing organ function [ 4], the patient population reviewed here is one of the most challenging for drug dosing [ 5, 6].
Was it most challenging?
What was most challenging?
Most challenging was the corruption.
Probably the most challenging.
Which image was most challenging to make?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com