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Most cellular components such as the cytoplasm, endosomes, lysosomes, endoplasmic reticulum, Golgi bodies, mitochondria, and nuclei are known to maintain their own characteristic pH values.
Because ROS are highly reactive, most cellular components are prone to oxidative damage.
Although most cellular components have been studied individually, the behavior of the cell emerges at the network-level and requires an integrative analysis.
More and more evidences from network biology indicate that most cellular components exert their functions through interactions with other cellular components, such as proteins, DNAs, RNAs and small molecules.
This was followed by a similar effort for human metabolism [19, 20], resulting in comprehensive representations of cellular metabolism in which most cellular components are unambiguously identified, a majority of which with ChEBI identifiers.
Most cellular components of the CAM are either blood vessels and capillaries or epithelial cells in direct contact to capillaries.
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GO analysis of essential genes identified organelle, intracellular membrane bound organelle (1022 and 946 genes in contrast to a random expectation of 701.5 and 607.1 genes respectively; P < 0.001) to be the most significant cellular components with most of the genes in nucleus (737 genes as against a random expectation of 392.3 genes; P < 0.001).
Using GO, ribonucleoprotein complex and ribosome were the most upregulated cellular components (C), and structural constituent of ribosome was the most upregulated molecular function (F) term.
Macrophages and other scavenger cells then engulf the membrane packets and process them for reuse as the most basic cellular components.
Membrane and related terms were the most downregulated cellular components (C) (Table S4).
The lipids are one of the most damaged cellular components by reactive oxygen species.
More suggestions(15)
most bioactive components
most abundant components
most other components
most damaging components
most cellular mRNAs
most necessary components
most common components
most cellular services
most cellular networks
most cellular oxidations
most important components
most efficient components
most vicious components
most cellular mechanisms
most cellular processes
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