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While stress is primarily sensed in most cells including neurons in the cytoplasm, the major attention of the lab has been on the nucleus.
Before plating, the bacterial suspension was thoroughly vortexed to ensure that most cells including possible cellular aggregates if any were uniformly dispersed.
The growth of most cells, including fibroblasts, requires integrin-mediated signals provided through attachment to a solid matrix.
High concentrations of N-SYN (5 and 10 µM) were found to be highly toxic, killing most cells, including glia (data not shown).
Staining with anti-TrkBex antibody, we found that most cells including YFP-positive cells expressed TrkB at 2 DIV (Fig. 4A).
In the male germ line, Dnmt2-EGFP was expressed in most cells, including stem cells as well as in maturing spermatocytes (Fig. 2E) with the exception of the post-mitotic hub cells (Fig. 2G).
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Note that because homologs are normally paired at high frequency in most Drosophila cells, including Kc cells, each unique FISH probe is expected to give only one spot in most nuclei.
Most differentiated cells, including cardiac myocytes, express multiple connexins.
Indeed, most PDAC cells, including KP-1N, express oncogenic Kras and it has been demonstrated that TGF-β-Smad pathway is activated in KP-1N cells [53].
Insulin and insulin like growth factor I (IGF-I) play critical roles in triggering pleiotropic actions including metabolism, proliferation and survival in most mammalian cells including the pancreatic islets [1].
It is important in this respect that most retinal cells, including the RPE are post-mitotic cells and that they are exposed to extremely high levels of oxidative stress over the prolonged period of (a life-) time.
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